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PUBLICATIONS

Long-read RNA sequencing identifies region- and sex-specific C57BL/6J mouse brain mRNA isoform expression and usage

Jones EF, Howton TC, Flanary VL, Clark AD, Lasseigne BN

Altered Glia-Neuron Communication in Alzheimer’s Disease Affects WNT, p53, and NFkB Signaling Determined by snRNA-seq

Soelter TM, Howton TC, Clark AD, Oza VH, Lasseigne BN

Signature reversion of three disease-associated gene signatures prioritizes cancer drug repurposing candidates

Fisher JL, Wilk EJ, Oza VH, Gary SE, Howton TC, Flanary VL, Clark AD, Hjelmeland AB, Lasseigne BN

Sex-biased gene expression and gene-regulatory networks of sex-biased adverse event drug targets and drug metabolism genes

Fisher JL, Clark AD, Jones EF, Lasseigne BN

The landscape of SETBP1 gene expression and transcription factor activity across human tissues

Whitlock JH, Wilk EJ, Howton TC, Clark AD, Lasseigne BN

Nucleic acid liquid biopsies in Alzheimer’s Disease: current state, challenges, and opportunities

Soelter TM, Whitlock JB, Williams AS, Hardigan AA, Hardigan AA, Lasseigne BN

Considerations and challenges for sex-aware drug repurposing

Fisher JL, Jones EF, Flanary VL, Williams AS, Lasseigne BN

Liquid biopsies in epilepsy: biomarkers for etiology, diagnosis, prognosis, and therapeutics

Whitlock JH, Soelter TM, Williams AS, Hardigan AA, Lasseigne BN

CoSIA: an R Bioconductor package for CrOss Species Investigation and Analysis

Haldar A*, Oza VH*, DeVoss N, Clark AD, Lasseigne BN

Cell-type-specific gene expression and regulation in the cerebral cortex and kidney of atypical Setbp1S858R Schinzel Giedion Syndrome mice

Whitlock JH, Oza VH, Soelter TM, Howton TC, Wilk EJ, Lasseigne BN

Rosalution: Supporting data accessibility, integration, curation, interoperability, and reuse for precision animal modeling

Uno-Antonison A, Fatima R, Scherer J, Moss A, Brown D, Foksinska A, Gajapathy M, Wilk EJ, Lasseigne BN, Worthey EA.

Inferring chromosomal instability from copy number aberrations as a measure of chromosomal instability across human cancers

Taluri S*, Oza VH*, Soelter TM, Fisher JL, Lasseigne BN*.

Computational advancements in cancer combination therapy prediction.

Flanary VL, Fisher JL, Wilk EJ, Howton TC, Lasseigne BN*.

Evaluating cancer cell line and patient-derived xenograft recapitulation of tumor and non-diseased tissue gene expression profiles in silico

Williams AS*, Wilk EJ*, Fisher JL, Lasseigne BN.

Quantifying transcriptome diversity: a review.

Jones JL, Haldar A, Oza VH, Lasseigne BN*.

Prioritized polycystic kidney disease drug targets and repurposing candidates from pre-cystic and cystic mouse Pkd2 model gene expression reversion

Wilk EJ, Howton TC, Fisher JL, Oza VH, Brownlee RT, McPherson KC, Cleary HL, Yoder BK, George JF, Mrug M, Lasseigne BN*.

CINmetrics: an R package for analyzing copy number aberrations as a measure of chromosomal instability

Oza VH, Fisher JL, Darji R, Lasseigne BN*.

Ten Simple Rules for Using Public Biological Data for Your Research

Oza VH, Whitlock JH, Wilk EJ, Uno-Antonison A, Wilk B, Gajapathy M, Howton TC, Trull A, Ianov L,

Worthey E, Lasseigne BN*.

Cell-type-specific alternative splicing in the brain and kidney of a Setbp1S858R Schinzel–Giedion syndrome mouse
Soelter TM, Jones EF, Howton TC, AB Crumley AB, Wilk EJ, Lasseigne BN

Impacts of Metabolic and Mitochondrial Reprogramming on ADPKD Drug Targets and Repurposing

Freeman J, Taluri S, Wilk EJ, Howton TC, Chumley P, Mrug M, Lasseigne BN

Evaluation of altered cell–cell communication between glia and neurons in the hippocampus of 3xTg‐AD mice at two time points

Soelter TM, Howton TC, Wilk EJ, Whitlock JH, Clark AD, Birnbaum A, Patterson DC, Cortes CJ, Lasseigne BN

Identifying and exploiting combinatorial synthetic lethality by characterizing adaptive kinome rewiring of EGFRvIII-driven glioblastoma

Lin B, Shelton SK, Smithberger E, Ziebro J, Skinner KR, Bash RE, Kirckman R, Stamper A, Butler M, Flores A, Angus SP, East MP, Cloughesy TF, Nathonson DA, Berens ME, Sarkaria JN, Binder ZA, O'Rouke DM, Howton TC, Lasseigne BN, Willey CD, Johnson GL, Hjelmeland AB, Furnari FB, Miller CR

Macrophage Accumulation and Cyst Expansion in Pkd2 , Ift88 , and Double Mutant Mouse Models

Li Z, Hombal RP, Wang J, Cheraka S, Howton TC, Zimmerman KA, Collawn JF, Andersen RS, Haycraft CJ, Croyle MJ, Parant JM, Lasseigne BN, Yoder BK

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