CoSIA: an R Bioconductor package for CrOss Species Investigation and Analysis

Preprint server: bioRxiv
Authors: Anisha Haldar, Vishal H. Oza, Nathaniel S. DeVoss, Amanda D. Clark, and Brittany N. Lasseigne

High throughput sequencing technologies have enabled cross-species comparative transcriptomic studies; however, there are numerous challenges for these studies due to biological and technical factors. We developed CoSIA (Cross-Species Investigation and Analysis), an Bioconductor R package and Shiny app that provides an alternative framework for cross-species transcriptomic comparison of non-diseased wild-type RNA sequencing gene expression data across tissues and species through visualization of variability, diversity, and specificity metrics.

Brittany Lasseigne – May 5, 2023