Ten simple rules for using public biological data for your research
Because Science.
Lasseigne Lab
updates
CINmetrics: An R package for chromosomal instability analysis
Liquid biopsies in epilepsy: biomarkers for etiology, diagnosis, prognosis, and therapeutics
A role for GLUT3 in glioblastoma cell invasion that is not recapitulated by GLUT1
We are back with another update! Thank you for taking the time to check in on how our lab is evolving and growing! It has been almost two years since our last update, so a lot has happened!
It has been an eventful eight months. Our first and most recent entry was posted in March of this year, and much has happened since then! While COVID-19 has had a tragic negative effect on the world around us, we have been very fortunate to have had plenty of positive events as well.
Recent posts
New Publication in Cancer Reports! Evaluating cancer cell line and patient-derived xenograft recapitulation of tumor and non-diseased tissue gene expression profiles in silico
New Publication in Cancer Reports! Inferring chromosomal instability from copy number aberrations as a measure of chromosomal instability across human cancers
New Publication in Molecular Medicine! Prioritized polycystic kidney disease drug targets and repurposing candidates from pre-cystic and cystic mouse Pkd2 model gene expression reversion
New Publication in Briefings in Functional Genomics! Quantifying transcriptome diversity Review
CoSIA R Bioconductor package and Shiny app for CrOss Species Investigation and Analysis (Preprinted & Under Review; available on Bioconductor)
Sex-biased gene expression and gene-regulatory networks of sex-biased adverse event drug targets and drug metabolism genes (Preprinted & Under Review)
Signature reversion of three disease-associated gene signatures prioritizes cancer drug repurposing candidates (Preprinted & Under Review)
Computational Advancements in Drug Repurposing for Cancer Combination Therapy Prediction (Preprinted & Under Review)
Evaluating cancer cell line and patient-derived xenograft recapitulation of tumor and non-diseased tissue gene expression profiles (Preprinted & In Revision)
Inferring chromosomal instability from copy number aberrations as a measure of chromosomal instability across human cancers (Preprinted & Under Review)
New Publication in PeerJ! CINmetrics an R package for analyzing copy number aberrations as a measure of chromosomal instability (CINmetrics is available on CRAN)
New Publication in PLOS Computational Biology! Ten simple rules for using public biological data for your research
Chromosomal Instability and PKD Drug Repurposing Preprints